Originally published October 12, 2005, in the News & Observer of Raleigh, NC

Clinication, Inc.

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Point-of-View

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New ways to take our medicine

By ADEE FEINSTEIN

Research Triangle Park - As the implementation date for Medicare's Part D prescription drug benefit approaches, seniors are inundated with information on available choices and registration deadlines.

While the debate over the cost and scope of prescription drug coverage continues, there is no argument that the availability of such drugs is key to the modern-day treatment of disease. Presumably, as seniors' access to vital medications improves, so will their ability to more effectively battle debilitating disease and chronic illness.

However, in order for drugs to be safe and effective, patients have to faithfully follow their prescribed plan- of-care. "Patient noncompliance," originally noted by Hippocrates, is a significant public health problem with an almost unbearable cost.

It is estimated that upwards of 125,000 Americans die every year as a direct result of not following prescribed physician orders. The General Accountability Office estimates that the direct annual cost of patient noncompliance to health insurers exceeds $100 billion. It is the cause of 10 percent of all hospitalizations and 23 percent of all nursing home admissions. Moreover, 21 percent of all prescriptions are never dispensed. Overall, about half of all ambulatory patients are "noncompliant."

Most Americans enjoy access to some of the best health care in the world, manifested in the education and skill of providers, in innovative technologies and in broad availability of sophisticated, effective drug therapies. This is especially true in the Triangle. So why are we noncompliant?

Numerous scientific studies consistently point to three reasons: Forgetfulness, misunderstanding of requirements and being asymptomatic.

Forgetfulness, is entirely understandable: as seniors with chronic conditions are faced with an ever- expanding medicine cabinet it is easy to appreciate the difficulties of managing complex regimens. And with physician encounters averaging eight minutes, it becomes impossible to properly educate a patient on key self-care issues.

Lastly, the asymptomatic patient has no pain or discomfort to compel adherence. It is no surprise that oral contraceptives have adherence rates which exceed 90 percent, while drugs that attack hypertension or high cholesterol have adherence rates of less than 50 percent.

It is painfully obvious that simply improving the overall availability of prescription medications via Medicare benefits or discount cards will not necessarily result in improved health outcomes and may even result in an increase in hospitalizations and nursing-home admissions, as more patients are left to fend for themselves in managing complex self-care requirements. Prescribing complicated regimens without proper education and ongoing surveillance is akin to providing patients with a scalpel and an instruction sheet for do-it-yourself surgery at home. A hazardous outcome is virtually guaranteed.

At the heart of the problem lies the traditional model for ambulatory care, in which physicians diagnose illness and provide consultative advice in the form of prescriptions and orders. There is typically little or no follow-up until the next office visit, when the effects of noncompliance may have already set in.

So how do we ensure that seniors are receiving the quality care they deserve while tax dollars are used in a cost-effective manner? The solutions may be closer to home than we realize.

Those of us who are caregivers to others with disease must take a more active role in educating ourselves as to the health care requirements of loved ones. We need to understand their medication regimens, monitor adherence and not hesitate to contact providers when questions or concerns arise.

The pharmaceutical industry, well represented in this region, needs to improve its efforts to discover and develop drugs whose format may improve adherence. For example, it is easier to be compliant if you have to take only one pill daily. Improved compliance equals increased drug sales.

Our universities and colleges should initiate research into methods to promote adherence, and medical schools can educate new physicians on the value of properly instructing and monitoring patients between visits.

Finally, health insurers must realize that the primary care physician is the person best suited to educate, advise and monitor the patient. Doctors should not be expected to provide these services for free, and new reimbursement methodologies need to be designed to properly compensate physicians for managing chronic patients' disease. After all, avoided hospitalizations greatly increase the financial viability and profitability of insurers. That, in turn, benefits their customers.

Only through measures such as these will seniors truly benefit from improved access to prescription medications. Merely flinging more drugs at people with disease may result in an outcome society can ill- afford.

Adee Feinstein is CEO of Clinication, Inc., an RTP-based health information technology developer.